Applications

Discover the wide breadth of possibilities with SPARTA®

SPARTA® has been successfully applied in a range of publications in leading academic journals such as Nature Communications, ACS Nano and Advanced Materials

SPARTA® General capabilities

Automated laser optical trapping combined with the power of Raman spectroscopy

Case study – Doxil®

SPARTA® analysis of liposomal formulation of doxorubicin

Case study – Coupling lipid nanoparticle structure and single-particle composition analysis to design enzyme-responsive nanocarriers

SPARTA® reveals how LNP composition and structure influence intracellular processing and function

Case study – Gene therapy vectors

SPARTA® analysis of lentiviral vectors – overcoming variation in vector performance

Case Study – Single-particle Raman analysis of extracellular vesicles as breast cancer biomarkers

A minimally invasive, more accurate approach to breast cancer detection using Raman spectroscopy

Case study – Hybrid polymer–lipid nanoparticles 

Optimising hybrid polymer–lipid nanoparticles for a novel malaria nanotherapy using SPARTA® 

Case study – Ethanol-guided hybridisation of extracellular vesicles with liquid-crystalline lipid nanoparticles

SPARTA® provides single-particle, label-free compositional confirmation of true EV–LCNP hybrid formation

Case study – Confirming true hybrid extracellular vesicles (HEVs) for mRNA delivery with single-particle, label-free analysis

SPARTA® reveals single-particle composition of HEVs to confirm extracellular vesicle (EV) and lipid nanoparticle (LNP) fusion

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